Sedimentological investigation of the late Paleoproterozoic (Orosirian) Vempalle Formation of the Cuddapah Basin, Dharwar craton, India, reveals three facies association that range from supratidal to deep subtidal. Sedimentary rocks of this succession are dominated by heterolithic carbonate mudstone, intraformational carbonate conglomerate, and a variety of columnar, domal, and stratiform microbialite facies. Deposition occurred in an extensional regime during development of a low-gradient ramp, where the distribution of microbialite facies is distinctly depth-partitioned. A gradual increase in synoptic relief of columnar stromatolites through the section, and the upward transition from stratiform to columnar microbialites, record a prolonged marine transgression with little or no influx of terrigenous detritus. Siliciclastic influx along the northeastern side of the shelf reflects the redistribution of topographic highs concomitant with large scale volcanic activity. Redistribution of topographic highs eventually led to progradation of peritidal facies and shutting down of the carbonate factory. Earthquake-induced ground shaking and voluminous volcanism experienced by this platform point to the reactivation of a deep-seated mantle-plume that resulted in thermal doming of the Dharwar crust prior to the onset of Cuddapah deposition. Isotopic and elemental chemistry of a selection of Vempalle Formation carbonate rocks record elevated Mn 2+ and Fe 2+ concentrations and depleted carbon isotope values in inner ramp lagoonal facies, relative to more open marine stromatolitic facies. Patterns of isotopic and elemental variation suggest the presence of geochemically distinct water masses—either within the water column or within substrate pore fluids—that resulted from a combination of globally low marine oxygenation and restricted oceanographic circulation in inner ramp environments. These data suggest that, even in the aftermath of Early Paleoproterozoic oxygenation, that ocean chemistry was heterogeneous and strongly affected by local basin conditions.