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It has been suggested that bone health in adulthood is programmed by development in utero. Most previous investigations addressing this topic have focussed on bone mineral density or content, rather than other indicators of bone health, such as biochemical markers of bone turnover. This study investigated whether potential predictors, from different stages of life, influence bone resorption in men...
Birth weight is positively associated with adult bone mass. However, it is not clear if its effect is already evident in early adulthood.To investigate the association between birth weight, adult body size, the interaction between them and bone mass in young adults.Bone densitometry by DXA was performed on 496 individuals (240 men) aged 23–24 years from the 1978/79 Ribeirão Preto (southern Brazil)...
Fracture risk is determined by bone mass, size and architecture. Birth weight (Bwt) is reported to predict adult bone mass and density. Early life environment may therefore be a determinant of bone strength in later life. However such evidence was obtained using dual energy X-ray absorptiometry (DXA), which is known to be dependent on size.We used peripheral quantitative computed tomography (pQCT)...
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