Bruyere O, Wuidart M-A, Di Palma E, Goulay M, Ethgen O, Richy F, Reginster J-Y. Controlled whole body vibration to decrease fall risk and improve health-related quality of life of nursing home residents. To investigate the effects of whole body vibration in the elderly. Randomized controlled trial. Nursing home. Forty-two elderly volunteers. Six-week vibration intervention plus physical therapy (PT) (n=22) or PT alone (n=20). We assessed gait and body balance using the Tinetti test (maximum scores of 12 for gait, 16 for body balance, 28 for global score), motor capacity using the Timed Up & Go (TUG) test, and health-related quality of life (HRQOL) using the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36). After 6 weeks, the vibration intervention group improved by a mean ± standard deviation of 2.4±2.3 points on the gait score compared with no score change in the control group (P<.001). The intervention group improved by 3.5±2.1 points on the body balance score compared with a decrease of 0.3±1.2 points in the control group (P<.001). TUG test time decreased by 11.0±8.6 seconds in the treated group compared with an increase of 2.6±8.8 seconds in the control group (P<.001). The intervention group had significantly greater improvements from baseline on 8 of 9 items on the SF-36 compared with the control group. Controlled whole body vibration can improve elements of fall risk and HRQOL in elderly patients.