In this research, UiO-66-NH2 was synthesized with solvothermal method and analyzed by XRD, SEM, BET, TGA and IR spectroscopy to understand its crystalline structure, morphology, thermal stability, and porous structure. Mass fraction of 0.1% of UiO-66-NH2 added to aqueous solution of mass fraction of 40% N-Methyldiethanolamine (MDEA). Measurement of zeta potential showed that UiO-66-NH2 particles are stable in aqueous mass fraction of 40% MDEA. The solubility of carbon dioxide investigated in aqueous solution of mass fraction of 40% MDEA and the prepared mixture of mass fraction of 0.1% of UiO-66-NH2 nanofluid in aqueous solution of mass fraction of 40% MDEA at temperatures of 303.15, 313.15, 323.15, and 333.15 K, and carbon dioxide pressures up to 2300 kPa. Results showed that addition of UiO-66-NH2 nanoparticles to the MDEA solution, increased capacity of CO2 absorption of solution up to 10%. The solubility of CO2 increased with increasing partial pressure and decreased with increasing temperature for both systems.