A sensitivity factor that quantifies the responsiveness of stomata to xylem sap abscisic acid concentration ([ABA] xyl ) is described, using the relation between [ABA] xyl and maximum leaf conductance (g max ). Plotting g max against this factor results in a common linear relationship for woody and herbaceous species from boreal to (semi-) arid climates. The global distribution of the sensitivity factor reveals an unexpected pattern which is inverse to rainfall, i.e., plants in humid climates respond more sensitively to ABA than plants in arid areas. The implications for the response of natural vegetation and consequences for agriculture are discussed.