The present paper deals with the thermophoresis particle deposition and Soret–Dufour effects on the convective flow, heat and mass transfer characteristics of an incompressible Newtonian electrically conducting fluid having temperature-dependent viscosity over a non-isothermal wedge in the presence of thermal radiation. The governing boundary layer equations are written into a dimensionless form by similarity transformations. The transformed coupled non-linear ordinary differential equations are solved numerically. The effects of various important physical parameters are analyzed in detail. It is found that the skin friction coefficient and the local Sherwood number increase with increase in the values of thermal radiation parameter in the presence of heat generation/absorption whereas reverse effect is seen on the local Nusselt number.