The frequency of cardiovascular disease (CVD) in the HD population is twice that of the general population. The study's purpose was to investigate the predictive value of lipid profiles and Body Mass Index (BMI) on morbidity (admits and length of stay (LOS) ) . Patients were stratified based on diabetic status (DM), hospitalizations, BMI, and ethnicity. Data (demographic, lipid parameters, and morbidity) were analyzed on 158 HD patients over a two year period. No correlation was found between atherogenic profiles and hospitalization admits/LOS. Serum cholesterol levels were higher in DM hospitalized patients when compared to non-DM patients. A significantly higher (p<0.05) number of admits/LOS were found among DM patients vs. non-DM patients (58%); however, they were not always related to CVD events. Body mass index values >30 were not predictive of admits/LOS. Patients with a BMI >30 had a higher (p<0.05) atherogenic profile. Diabetic patients had a higher overall BMI than non-DM patients. Triglyceride (TG) levels were significantly higher (p<0.01) in non-black patients. It was concluded that 1) Atherogenic profiles were not predictive of admits/LOS, 2) Diabetic patients had higher cholesterol levels and admits/LOS vs. non-DM patients, but underlying causes may be CVD related, 3) The ethnic differences in TG levels may be affected by the theory on insulin resistance and vascular changes.