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Objective. The objective of this study was to determine whether there is a link between integrins and components of the plasminogen system, regarding tumor cell invasion to the artificial extracellular matrix.Methods. Immunocytochemistry was performed with antibodies directed against integrins α 2 β 1 , α 4 β 1 , α 5 β 1 , α 6 β 1 , and...
Objective. The goal of this work was to evaluate the involvement of gonadotropins in the regulation of adhesion of human epithelial ovarian carcinoma. We studied two pathways that were previously implicated in the metastatic implantation of ovarian carcinoma to the peritoneum, namely hyaluronan-CD44 and RGD-integrin mediated adhesion.Methods. Two cell lines derived from human epithelial ovarian carcinoma...
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