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Chitosan was N-acylated with butanoic, hexanoic and benzoic anhydride under homogeneous conditions in the presence of methanol. The degree of substitution of N-acyl chitosans was determined by 1 H-NMR. The N-acyl chitosan nanoparticles were prepared by the addition of tripolyphosphate anions. Freeze-dried N-acyl chitosan nanoparticles were then analyzed for particles size, zeta potential,...
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