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Advances in Vitamin D nutritional physiology since publication of the DRIs in 1997 are briefly summarized. Available data indicate that (1) Vitamin D's canonical function, optimizing intestinal calcium absorption, is fully expressed at serum 25-hydroxyvitamin D (25OHD) concentration of ∼80nmol/L; (2) elevated parathyroid activity, typical of aging populations, is minimized at the same 25OHD value...
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