The chiral ligand mediated enantioselective reaction of methyllithium with furylimines was investigated in the presumed 1,4- and 1,2-addition manners. The imines bearing a phosphinoyl or sulfonyl group on the imine nitrogen atom gave rather poor enantioselectivity. On the other hand, the imines bearing a 2-substituted anisidine moiety were found to be the appropriate substrate, giving the corresponding amines with up to 91% ee.