This investigation examined the relationship between family environment and mean arterial pressure in a sample of African-American youth. Completed data were collected from 46 adolescents attending an inner-city junior high school. Blood pressure measurements were assessed in a seated position with a Dinamap 1846 Vital Signs Monitor. To assess the additive effects associated with the family environment, a composite risk score (cohesion, conflict, control, and organization subscales of the Family Environment Scale) was computed. Regression analyses indicated that the cumulative risk associated with the family environment was predictive of resting mean arterial pressure.