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Baclofen, a GABA B agonist, reduces ethanol intake in animals and humans, but the contrary or no effect was also reported. Our previous study demonstrated that mice characterized as “loss of control over ethanol intake” had different Gabbr1 and Gabbr2 transcription levels, which express, respectively, the GABA B1 and GABA B2 subunits in brain areas related to addictive behavior...
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