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The Desmoglein 3 (Dsg3) knockout mouse and pemphigus vulgaris (PV) mouse model present a similar type of supra-basal acantholysis, even though the subcellular mechanism is considered to be completely different.To detect changes in the desmosomal molecular composition in Dsg3−/− mice and PV model mice to highlight the precise mechanism for acantholysis at an ultrastructural level.Using epithelia from...
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