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Current targeted therapy proves no effective outcomes in lung squamous cell carcinoma (SQCC). Recent studies suggested that FGFR1 would be promising. This systematic review elaborated FGFR1 amplification in lung SQCC.An electronic search was conducted on PubMed, EMBASE, Web of SCI, Google Scholar and Cochrane Library. Eligible studies regarding incidence of FGFR1 amplification in lung SQCC and correlation...
There is renewed interest in performing segmentectomies and wedge resections for selected patients with early-stage non-small cell lung cancer. However, comparative data on sublobar resections versus lobectomies include ‘intentionally selected’ patients who could tolerate either procedure, or ‘compromised’ patients who could only undergo sublobar resections due to significant comorbidities or insufficient...
Although maintenance therapy has been a routine treatment paradigm for advanced non-small cell lung cancer (NSCLC), there is currently lack of direct evidence to identify patients most likely to benefit from maintenance therapy for advanced NSCLC.Trials comparing maintenance therapy with placebo or observation in NSCLC were identified. The primary endpoint was overall survival (OS) in trial population...
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