We describe a case of a 75 year old man diagnosed 14 years previously with a lentigo maligno melanoma (level IV to Clark's classification). The elective treatment was surgery and immuno stimulants like BCG. Two years later he had small pigmentated lesions on the nose. The diagnosis was metastasis of melanoma (Clark III) . The treatment was excision of the lesion by surgery. One year later the patient returned with metastases in the left submaxillary lymph node the treatment was surgery with lymph node dissection and bovine thymus derivates. Six months later the patient was treated with systemic chemotherapy with DTIC (3 courses). The follow up was good until three months ago when the patient come to us for the first time and presented a pigmented, indented, irregular lesion of 2 2 and also irregularity of colour within the tumour itself, localizated on the nose near the first lesion mentioned above. The diagnose was again a superficial spreading melanoma (Clark III) with vertical growth phase, and treated with surgery and nasolabial flap.