Weight deduction is one of the key steps in full-scale aircraft static strength test. It will keep the experimental craft zero-gravity during the full-scale aircraft static strength test and fatigue strength test to make the test status as real flight condition of the plane more truly. In consideration of the necessary and benefit of weight deduction, a complete scheme of weight deduction in full-scale aircraft static structural test was presented, which including the method for calculating the weight of test piece, method for deducting the weight of test piece and loading device and the design of the weight deduction device. The full-scale static strength test of one type of aircraft was used as research object. The test was successfully completed and valid test result was obtained by deducting the weight of test piece and loading device based on the above-mentioned scheme. The result shows that the method for calculating weight deducted is scientific and logical, and the weight deduction scheme is viable. The proposed scheme could deduct the weight of test piece and loading device effectively, reduce the weight effect on test results and has important reference value to similar test.