The experimental excess molar enthalpy, H m E , data are reported for 1-alkanols (2), namely, {methanol, ethanol, 1-propanol, 1-butanol and 1-pentanol} in cyclopentanone (1) at T=298.15K and ambient pressure over a whole range of mole fractions. The values of H m E data are positive over the whole range of mole fraction and the magnitude of H m E data also increases with increasing chain length of 1-alkanols. The Peng–Robinson–Stryjek–Vera (PRSV) equation of state (EOS) has been used to predict the experimental H m E data. As a comparison with PRSV EOS, the ERAS-model was applied for simulation of the experimental excess molar enthalpy to describe the experimental H m E data.