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New and old data pertinent to the electrochemical potentials across the inner mitochondrial membrane are reviewed with the intent of reconciling the various findings in the light of new perspectives provided by more recent knowledge. A careful scrutiny of old data permits ruling out the presence of a significant metabolically dependent electrical membrane potential. Recent technological advances make...
All evidence presently available shows that there is no metabolically dependent electric potential (ΔΨ) across the mitochondrial inner membrane. The data supporting this statement are documented in our review article and in the present communication. The evidence purported to show a ΔΨ results from a miscalculation or the mistaken assumption that the distribution of lipophilic cations is in response...
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