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Equilibrative nucleoside transporters (ENT) modulate the flux of adenosine. The ENT1-null (KO) mouse heart is endogenously cardioprotected but the cellular basis of this phenotype is unknown. Therefore, we investigated the cellular mechanisms underlying ENT1-mediated cardioprotection.Circulating adenosine levels were measured in WT and KO mice. Cellular levels of nucleosides and nucleotides were investigated...
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