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To determine the effects of food restriction (FR) on the expression of Sirt1 and its down-stream factors related to lipid and glucose metabolism in obese and hypertensive rats (SHRSP/IDmcr-fa), as a model of human metabolic syndrome.Male, 10-week-old SHRSP/IDmcr-fa rats were treated with 85% FR for 2weeks. Metabolic parameters, serum adipocytokines and distribution of serum adiponectin multimers were...
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