To evaluate the effect of Pyonex in treatment of patients with delayed gastric emptying after esophagectomy. Twenty-three patients were treated with Pyonex at Píshū ( BL 20, bilateral), Wèishū ( BL 21, bilateral), Nèiguān ( PC 6), Zúsānlľ ( ST 36), Sānyīnjiāo ( SP 6) and Shídào ( CO 2) on the basis of conventional treatment. The pyonexs were changed every four days, and change for five times was considered as one course of treatment. The efficacy was evaluated after treatment for one course. One patient was cured after treatment for one time, with the effective rate of 4.4%; two patients were cured after treatment for two times, with the effective rate of 8.7%; ten patients were cured after treatment for three times, with the effective rate of 44.5%; seven patients were cured after treatment for four times, with the effective rate of 30.4%; and three patients were cured after treatment for five times, with the effective rate of 13.0%. 23 patients were cured after treatment for five times, with the total effective rate of 100%. Pyonex has sound effect in treatment of patients with delayed gastric emptying after esophagectomy.