The Active Compression-Decompression CPR (ACD-CPR) is one of the promising methods of life support, however its beneficial effect is still not proved by controlled clinical trials. In our department the guideline for resuscitation includes chest compressions according to the recommendations of the European Resuscitation Council. Nevertheless, in some cases when the efficacy of chest compressions is considered to be poor or progressively decreasing we do offer to continue ACD-CPR using the AMBU CARDIOPUMP device.A 65 years old patient was admitted to our department with a completed stroke and subacute myocardial infarction. Haemodynamical monitoring was carried out by pulmonary catheterization. Since this catheter was not appropriate for thermodilution CO measurements, we used transoecophageal doppler (ODM) method. Continuous arterial blood pressure, transcutaneous oxygen saturation and ETCO2 were also monitored. We were not able to stabilize the haemodyniamical status and a cardiac arrest was caused by VF. The witnessing nurse initiated life support, and then advanced life support was carried out for 30 minutes. Since the haemodynamical effect of the chest compressions were considered to be poor we started to use CARDIOPUMP. During the whole resuscitation the haemodynamical parameters were registered. There was a short period of ROSC, followed by another VF and then asystolia so the resuscitation efforts were withheld after the 30th minutes of arrest.The evaluation of the registered haemodynamical parameters provided information about the efficacy of the resuscitation attempt. We found that the haemodynamical effect of chest compressions depends on the quality of compressions. This difference emphasizes the importance of training. The MABP but also the CO was significantly higher after the administration of epinephrine, when a maximum of 66 mmHg of MABP and 9 l/min of CO were achieved for a short period of time. During the ACD-CPR, the highest CO was 10.4 l/min and the MABP was 73 mmHg. The recovery of the spontaneous circulation was registered in the 4th minute of ACD-CPR, after a DC shock of 360 Ws. (A total of 12 DC shock were delivered by that time). When the second arrest occurred, the first DC shock turned the VF into asystolia. During standard chest compressions a progressively decreasing circulation was recorded. ACD-CPR was installed again, and rised the MABP to 52 mmHg from 38 mmHg and the CO to 8.1 l/min from 4.3 l/min. Meanwhile the end tidal CO2 rised again, but after 4 minutes of ACD-CPR the MABP, the CO and also the ETCO2 had fallen down and the asystolia persisted.These results cannot be compared to other clinical investigations since neither the circumstances nor the haemodynamical monitoring were standardized. However, we found that the ODM seems to be an easily applicable method for continuos CO measurement even during CPR. The use of CARDIOPUMP could improve the CO and MABP but was unable to restore the function of the multiply injured myocardium in this case.