The purpose of this study was to determine the effects of synthesized sodalite zeolite infiltration achieved by a direct in-situ hydrothermal reaction followed by sintering process on the flexural strength and hardness of alumina and zirconia-toughened alumina (ZTA) frameworks. Ceramic core materials were prepared as disk-shaped specimens with 16mm diameter and 1.2±0.2mm thickness. The case-study group was synthesized sodalite zeolite-infiltrated alumina (IA-SOD) and synthesized sodalite zeolite-infiltrated ZTA (IZ-SOD); and the control group was glass-infiltrated alumina (IA-glass) and glass-infiltrated ZTA (IZ-glass). The biaxial flexural strength (piston-on-three-balls test) and Vickers microhardness were compared among groups (n=10 specimens in each group). Scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX) were used to investigate the structural characteristics of specimens at the fracture and cross-sectional surfaces. For both IA-SOD and IZ-SOD, the biaxial flexural strength exceeded the required value of 100–150MPa as specified by ISO 6872(2015), indicating their potential as all-ceramic core materials. The flexural strengths and Vickers microhardness of IZ-SOD were respectively 324.7MPa and 1162 VHN, while these values were measured 233.6MPa and 1013 VHN for IA-SOD. The mechanical properties and microstructure of core materials have been advocated as crucial to the clinical performance of all-ceramic dental restorations. This investigation provides data regarding the flexural strength, hardness and microstructure of partially sintered alumina and ZTA frameworks with synthesized sodalite zeolite infiltration.