The microstructural evolution and the flow behavior of Ti–6Al–1.5Cr–2.5Mo–0.5Fe–0.3Si alloy were investigated in this research. The flow behavior of the alloy at temperatures in the range of 100–600°C was studied using warm compression testing under the strain rate of 0.001–0.1s−1. The results indicate that the formability of the alloy is significantly increased at temperatures higher than 400°C due to the activation of pyramidal slip systems. Moreover, optical observations confirm the occurrence of flow localization and adiabatic shear banding within the microstructure due to the adiabatic heating phenomenon at lower temperatures. The adiabatic heating is also led the experimental material to exhibit a negative strain rate sensitivity behavior. The tensile deformation behavior of this alloy was also studied at temperatures in the range of 100–400°C through warm tension testing. The results show that the alpha phase grains are elongated along the tensile direction at lower temperatures but would be globularized at higher temperatures.