A powder metallurgy route based on hot isostatic pressing (HIP) of tape-cast monotapes was used for the direct fabrication of dense thin sheets (250–300μm thick) of gamma titanium aluminide (γ-TiAl). Polarized light microscopy revealed a fine-grained microstructure (average grain size ∼3μm) but a few isolated larger grains (∼20μm) were also present. The primarily metastable α 2 microstructure of the rapidly solidified starting powder transformed to the equilibrium near-γ microstructure during HIP at 1100°C. Chemical analysis revealed that the dense sheet had a carbon content of 0.13wt.%, which was only 0.04wt.% higher than that of the starting powder, but the oxygen content was significantly higher, presumably introduced during the decanning step. The hardness measured using Vickers microindentation technique was 384±9HV. Manipulation of the as-HIPed microstructure was performed by heating for up to 1h in flowing argon at temperatures (1170–1385°C) below and above the alpha transus (1355°C). Below 1250°C, limited grain growth and no discernable change in the as-HIPed (near-γ) microstructure occurred. Sheets heated to 1320°C and 1365°C had a duplex microstructure of γ and α 2 grains, with some lamellar grains. Except for a thin surface layer (20–30μm thick), the microstructure of the heat-treated sheet was uniform, but a fully lamellar microstructure was not achieved even after heating for 1h at 1385°C.