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d-Glucosamine has been widely reported to have immunosuppressive actions on neutrophils, lymphocytes, and other cells of the immune system. However, under conditions used in biological experiments (e.g., neutral pH, and phosphate buffers), we have found that d-glucosamine self-reacts to form 2,5-deoxyfructosazine [2-(d-arabino-tetrahydroxybutyl)-5-(d-erythro-2,3,4-trihydroxybutyl)pyrazine] (1) and...
The high molecular weight of chitosan, which results in a poor solubility at neutral pH values and high viscosity aqueous solutions, limits its potential uses in the fields of food, health and agriculture. However, most of these limitations are overcome by chitosan oligosaccharides obtained by enzymatic hydrolysis of the polymer. Several commercial enzymes with different original specificities were...
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