The solid–liquid distribution coefficient (K d ) is the parameter that governs the incorporation of contaminants in soils. Its estimation allows the prediction of the fate of contaminants in the short- and long-term after a contamination event. Here, the K d of radiostrontium (K d (Sr)), a radionuclide of significant environmental interest, was predicted by hard models, which are based on knowledge of the mechanisms governing its sorption, and by soft models based on Partial Least Squares (PLS), using a large data set with the main soil parameters. The two approaches were tested and compared for 30 soils in Spain. Correlations between the predicted and experimental values of K d (Sr) obtained using hard- and soft-modelling showed slopes close to 1 and regression coefficients higher than 0.95, which confirms that both approaches are able to obtain satisfactory estimates for K d (Sr) from soil parameters.