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Biomechanical responses of chondrocytes were determined in specific locations within the superficial zone of patellar, femoral groove, femoral condyle and tibial plateau cartilages obtained from female New Zealand White rabbits. A confocal laser scanning microscope combined with a custom indentation system was utilized for experimentation. Changes in cell volumes and dimensions (i.e. cell height,...
Relationships between cartilage structure and superficial in situ chondrocyte deformations were investigated from 6 different knee joint locations (n=10 knees). Depth dependent cartilage structure and composition were quantified with microscopic/microspectroscopic methods. Medial tibial cartilages had the lowest superficial collagen content, highest collagen orientation angle, and highest proteoglycan...
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