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Objective: To examine whether low-grade cervical dysplasia carries a higher risk of progression when associated with the cancer-related human papillomavirus types 16, 18, 31 or 33. Study design: Retrospective, with PCR-based HPV diagnosis on the original cervical biopsies from 71 patients with CIN I and II. CIN III developed in 34 lesions, and 37 showed complete regression during non-invasive follow-up...
Detection of high risk human papillomaviruses (HPV) has a high potential value for secondary prevention of cervical cancer. HPV testing can augment the sensistivity of conventional cytologic screening and can be used for triaging patients with a history of mild cytological abnormalities or low grade cervical intraepithelial neoplasia (CIN). Before screening for high risk HPVs can be generally recommeended,...
Thirty two pregnant women, immune to human cytomegalovirus (HCMV) before conception, were examined with a combination of amniocentesis, and blood sampling for fetal HCMV infection. The pregnant women had no history of recurrent infection and they all had normal ultrasonographic findings. Maternal sera and amniotic fluids were examined for anti-HCMV antibodies and viral DNA by enzyme immunoassay and...
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