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The proliferation and/or survival of a variety of cells is dependent on cellular hydrogen peroxide (H 2 O 2 ) production. We tested whether this was true of leukemic cells, using cell lines from leukemic patients (CEM, 697, Mn-60, and Tanoue). We found that addition of catalase inhibited proliferation of all cell lines and induced death in two. However, this turned out to be due to...
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