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HO * attack on hyaluronic acid, related polymers and monomers has been studied by both direct, rapidflow, EPR (ESR) and EPR spin trapping using a variety of traps. Evidence has been obtained, with the monomers, for essentially random hydrogen-atom abstraction at all the ring C--H bonds with glucuronic acid, and at all sites except the N-acetyl side chain and C(2) with N-acetylglucosamine...
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