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Preeclampsia is a pregnancy-specific disorder associated with hyperlipidemia. Liver X receptor (LXR) α and LXRβ are key regulators of lipid homeostasis. In the current study, we investigated expression of LXRα, LXRβ and their target genes in human term placenta, decidua and subcutaneous adipose tissue from pregnancies complicated by preeclampsia. Furthermore, we analyzed the protein levels of LXRα...
This study investigated the development of adipose tissue in the guinea pig and the impact of maternal undernutrition on the structural and functional characteristics of perirenal adipose tissue in the dam and fetus. Date-mated guinea pigs were provided with either ad libitum feed (Control, C) or 85% of food intake per body weight of the Controls (Undernutrition, UN). Maternal (C, n = 6; UN, n = 7)...
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