Neuroscience & Biobehavioral Reviews

Items from 1 to 7 out of 7 results

article

Liability to substance use disorders: 1. Common mechanisms and manifestations

Michael M. Vanyukov, Ralph E. Tarter, Levent Kirisci, Galina P. Kirillova, more

Neuroscience and Biobehavioral Reviews > 2003 > 27 > 6 > 507-515

Variation in the risk for and severity of substance use disorders (SUD) in the population is caused by multiple organismic (genetic, biochemical, psychological) and environmental factors. Whereas drug- or drug-class-specific liability mechanisms exist, a substantial proportion of variance in the risk is shared between specific liabilities, reflecting mechanisms that determine common liability to SUD...

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Neuroscience and Biobehavioral Reviews > 2003 > 27 > 6 > CO2

article

The interpretation of the measurement of nucleus accumbens dopamine by in vivo dialysis: the kick, the craving or the cognition?

Michael H. Joseph, Krishna Datla, Andrew M.J. Young

Neuroscience and Biobehavioral Reviews > 2003 > 27 > 6 > 527-541

Psychopharmacological studies have implicated the dopaminergic innervation of the nucleus accumbens (NAC) in reward and reinforcement, in the actions of addictive drugs, and in the control of the symptoms of schizophrenia. Recent developments in in vivo dialysis, and other in vivo neurochemical techniques have permitted a more direct analysis of the behavioural correlates of increased dopamine release...

article

Amygdalar control of the mesocorticolimbic dopamine system: parallel pathways to motivated behavior

Anthony G. Phillips, Soyon Ahn, John G. Howland

Neuroscience and Biobehavioral Reviews > 2003 > 27 > 6 > 543-554

The present review focuses on recent findings from our laboratory showing that there are major differences in the influence exerted by the central (CeN) and basolateral (BLA) nuclei of the amygdala on dopamine (DA) efflux in the nucleus accumbens (NAc) of the rat. Based on these data, we propose that the CeN maintains control, via an indirect pathway, of the tonic activity of a population of ventral...

article

The medial prefrontal cortex in the rat: evidence for a dorso-ventral distinction based upon functional and anatomical characteristics

Christian A. Heidbreder, Henk J. Groenewegen

Neuroscience and Biobehavioral Reviews > 2003 > 27 > 6 > 555-579

The prefrontal cortex in rats can be distinguished anatomically from other frontal cortical areas both in terms of cytoarchitectonic characteristics and neural connectivity, and it can be further subdivided into subterritories on the basis of such criteria. Functionally, the prefrontal cortex of rats has been implicated in working memory, attention, response initiation and management of autonomic...

article

Liability to substance use disorders: 2. A measurement approach

Michael M. Vanyukov, Levent Kirisci, Ralph E. Tarter, Howard F. Simkevitz, more

Neuroscience and Biobehavioral Reviews > 2003 > 27 > 6 > 517-526

Liabilities to complex disorders, discussed in the accompanying paper, present difficulties in measurement related to the arbitrariness of diagnostic threshold definitions and problems with discrimination between trait values, especially within the 'normal' individuals. The inability to quantitatively estimate the risk for a disorder, such as substance use disorders (SUD), is an obstacle for studying...

article

Analysis of neurological disease in four dimensions: insight from ALS-PDC epidemiology and animal models

C.A. Shaw, J.M.B. Wilson

Neuroscience and Biobehavioral Reviews > 2003 > 27 > 6 > 493-505

The causal factor(s) responsible for sporadic neurological diseases are unknown and the stages of disease progression remain undefined and poorly understood. We have developed an animal model of amyotrophic lateral sclerosis-parkinsonism dementia complex which mimics all the essential features of the disease with the initial neurological insult arising from neurotoxins contained in washed cycad seeds...

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27
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2003

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Keywords

DOPAMINE (3)
ADDICTION (2)
COMPLEX TRAITS (2)
DRUG ABUSE (2)
ETIOLOGY (2)
MEDIAL PREFRONTAL CORTEX (2)
NUCLEUS ACCUMBENS (2)
PHENOTYPE (2)
SUSCEPTIBILITY (2)
VULNERABILITY (2)
ACETYLCHOLINE (1)
ALZHEIMER'S DISEASE (1)
AMYOTROPHIC LATERAL SCLEROSIS (1)
AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM DEMENTIA COMPLEX (1)
ANIMAL MODEL (1)
ANTERIOR CINGULATE CORTEX (1)
ATTENTION (1)
BASOLATERAL AMYGDALA (1)
CENTRAL AMYGDALA (1)
CYCAD (1)
ELECTRICAL STIMULATION (1)
EXCITOTOXICITY (1)
FEEDING (1)
INFRALIMBIC CORTEX (1)
ITEM RESPONSE THEORY (1)
LIDOCAINE (1)
MOTIVATION (1)
NEURODEGENERATION (1)
NOREPINEPHRINE (1)
PARKINSONISM (1)
PRELIMBIC CORTEX (1)
REINFORCEMENT (1)
REWARD (1)
SATIETY (1)
SCALE (1)
SEROTONIN (1)
STEROL GLUCOSIDE (1)
TIME COURSE (1)
TRANSIENT LESIONS (1)
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Neuroscience & Biobehavioral Reviews

Liability to substance use disorders: 1. Common mechanisms and manifestations

Editorial Board

The interpretation of the measurement of nucleus accumbens dopamine by in vivo dialysis: the kick, the craving or the cognition?

Amygdalar control of the mesocorticolimbic dopamine system: parallel pathways to motivated behavior

The medial prefrontal cortex in the rat: evidence for a dorso-ventral distinction based upon functional and anatomical characteristics

Liability to substance use disorders: 2. A measurement approach

Analysis of neurological disease in four dimensions: insight from ALS-PDC epidemiology and animal models

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