During “Mineral CO2 sequestration” the CO2 is chemically stored in solid carbonates by the carbonations of minerals. The sequestration of CO2 is permanent and safe. Mineral carbonation is an exothermic reaction and occurs naturally in the subsurface as a result of fluid–rock interactions within serpentinite. In situ carbonation aims to promote these reactions by injecting CO2 into porous, subsurface geological formations. In the northern sector of the Pollino Massif (southern Italy) extensively occur serpentinites; they are the subject of a project devoted to their possible use for in situ geological sequestration of CO2.