Fluorination of [60]fullerene dispersed in a CoF 2 matrix with molecular fluorine was studied. The reaction was carried out in a mass spectrometer. The partial pressures of volatile products were continuously monitored at the constant fluorine inlet. The differences in the activation barriers of subsequent fluorination from C 60 to C 60 F 44 were estimated. The conditions, at which C 60 F 18 and C 60 F 36 were formed selectively, were found. Based on a comparison between the fluorination of pure C 60 and C 60 dispersed in CoF 2 matrix, the role of a matrix in the selectivity of this process was elucidated.