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Substance P (SP)-containing terminals and SP receptors (SPRs) are found on the dendrites of preganglionic sympathetic neurons (PSNs) in the intermedio-lateral nucleus (IML) of the spinal cord. The SP-containing fibers were thought to be of supraspinal origin. However, the primary sensory nerve fibers terminated around PSNs, and some of them directly on PSNs. We observed approximately 150 SPR-immunoreactive...
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