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In view of biological activities of both 1,3-dioxolanyl nucleosides and C-nucleosides, d- and l-1,3-dioxolanyl C-nucleosides have been synthesized as potential antiviral and/or anticancer agents. Asymmetric synthesis of four new optically pure d- and l-1,3-dioxolanyl triazole C-nucleosides has been accomplished via key intermediate 5a and 5b starting from d- and l-2,3-O-isopropylidene glyceraldehyde...
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