A chemical solution deposition process was used to grow epitaxial Nd 2 Mo 2 O 7 (NMO) buffer layers on YSZ substrates to produce YBa 2 Cu 3 O 7−δ (YBCO) coated conductors. The NMO precursor solution prepared using metal acetylacetonates was spin-coated onto single crystal YSZ substrate of 10mm×10mm in size at 3000rpm for 30s and heat-treated at 1000°C for 2h in Ar after calcinated at 550°C for 1h. The YBCO film was deposited by TFA-MOD route on top of the NMO/YSZ architecture. The phase purity and the crystalline orientation of NMO and YBCO films were evaluated by X-ray diffraction (XRD). Scanning electron microscopy (SEM) and atomic force microscopy (AFM) were used to observe their microstructure and their surface roughness. The critical current density (J c ) of YBCO film on NMO/YSZ is 1.8MA/cm 2 at 77K in self-field, which indicates that the Nd 2 Mo 2 O 7 is a potential buffer for YBCO coated conductor.