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To assess the value for money of alternative chemotherapy strategies for managing advanced colorectal cancer using irinotecan or oxaliplatin, either in sequence or in combination with fluorouracil. A cost-effectiveness model was developed using data from the UK fluorouracil, oxaliplatin, and CPT11 (irinotecan) – use and sequencing (FOCUS) trial. The analysis adopted the perspective of the UK National...
To estimate the cost-effectiveness of cetuximab monotherapy, cetuximab plus irinotecan, and panitumumab monotherapy compared with best supportive care (BSC) for the third and subsequent lines of treatment of patients with Kirsten rat sarcoma wild-type metastatic colorectal cancer from the perspective of the UK National Health Service.An “an area under the curve” cost-effectiveness model was developed...
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