A low Reynolds number k- CFD model has been used for the description of flow pattern near the wall. An excellent agreement has been shown between the predicted and experimental hold-up and velocity profiles over a wide range of superficial gas velocity (V G ), column diameter (D), column height (H D ) and the nature of gas-liquid system (bubble diameter and their rise velocity). The CFD model has been extended for the prediction of pressure drop for two-phase gas-liquid flows in bubble columns. A comparison has been presented between the predicted and the experimental data over a wide range of superficial gas and liquid velocities and for three gas-liquid systems.