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A new, hybrid type of ultra-sensitive electrophysiological superoxide anion (O 2− ) sensor is described, which is based on “membrane-engineered” mammalian cells immobilized in an alginate matrix. The membrane-engineering process involved the electroinsertion of superoxide dismutase (SOD) molecules in the membranes of Vero fibroblast cells, which acted as catalytic units able to convert...
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