Positron annihilation lifetime spectroscopy measurements were performed on neutron-irradiated low carbon arc cast Mo. Irradiation took place in the high flux isotope reactor, Oak Ridge National Laboratory, at a temperature of 80±10°C. Neutron fluences ranged from 2×10 21 to 8×10 24 n/m 2 (E>0.1MeV), corresponding to displacement damage levels in the range from 7.2×10 −5 to 2.8×10 −1 displacements per atom (dpa). A high density of submicroscopic cavities was observed in the neutron-irradiated Mo and their size distributions were estimated. Cavities were detected even at a very low-dose of ∼10 −4 dpa. The average size of the cavities did not change significantly with dose, in contrast to neutron-irradiated bcc Fe where cavity sizes increased with increasing dose. It is suggested that the in-cascade vacancy clustering may be significant in neutron-irradiated Mo, as predicted by molecular dynamics simulations.