Integration of renewable energy based distributed generation (DG) units provides potential benefits to conventional distribution systems. The power injections from renewable DG units located close to the load centers provide an opportunity for system voltage support, reduction in energy losses, and reliability improvement. Therefore, the location of DG units should be carefully determined with the consideration of different planning incentives. This paper presents a comparison of novel, combined loss sensitivity, index vector, and voltage sensitivity index methods for optimal location and sizing of distributed generation (DG) in a distribution network. The main contribution of the paper is: (i) location of DGs based on existing sensitivity methods, (ii) proposing combined power loss sensitivity based method for DG location, (iii) modified Novel method for DG location, (iv) comparison of sensitivity methods for DG location and their size calculations, and (v) cost of losses and determining cost of power obtained from DGs and the comparison of methods at unity and lagging power factors. The results show the importance of installing the suitable size of DG at the suitable location. The results are obtained with all sensitivity based methods on the IEEE 33-bus and 69-bus systems.