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We have used P19 embryonal carcinoma cells as in vitro model for early neurogenesis to study ionotropic P2X and metabotropic P2Y receptor-induced Ca 2+ transients and their participation in induction of proliferation and differentiation. In embryonic P19 cells, P2Y 1 , P2Y 2 and P2X 4 receptors or P2X-heteromultimers with similar P2X 4 pharmacology were responsible...
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