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The use of biodegradable poly (D,L-lactide-co-glycolide) microparticles containing antigen (PLGA) as oral antigen delivery vehicles in pre-smolt Atlantic salmon (Salmo salarL.) was investigated. Test antigen, human gamma globulin (HGG), was dispersed within the copolymer matrix of the PLGA microparticles at a theoretical loading of 24% (w/w). Two polymer ratios were used (85:15 and 50:50 lactide:glycolide)...
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