In this work the reaction kinetics for pyridine hydrodenitrogenation on (Ni)WP/SiO 2 catalysts were determined. The experiments were conducted at 17.2bar and between 573K and 633K for various flow rates of hydrogen and pyridine. Adding Ni to the WP/SiO 2 catalyst enhanced the hydrogenation reaction and gave higher pentane and pentylamine yields. A trend in terms of selectivity was not evident on either catalyst. The results were fit to several models and a Bayesian approach was applied for parameter estimation and model discrimination. Adding Ni to the WP/SiO 2 catalyst did not change the reaction mechanism – both catalysts favor the same Langmuir–Hinshelwood model with different active sites for hydrogenation and CN bond cleavage. Ni did, however, influence the type of adsorbed species, the heat of adsorption and the activation energies.