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MAK-V/Hunk is a MARK/Par-1-related protein kinase, whose function is unknown. We studied the subcellular localization of MAK-V/Hunk in COS-1 cells by immunofluorescence. It has a nucleocytoplasmic distribution and is localized to the centrosome, as indicated by co-localization with γ-tubulin. A putative kinase-deficient mutant, with a mutation in the invariant lysine residue in the catalytic domain,...
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