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ORF 5 encoding the primary envelope glycoprotein, VP-3P, of a highly neuropathogenic isolate of lactate dehydrogenase-elevating virus (LDV-v) has been sequenced. It exhibits 92% nucleotide identify with the ORF 5 of an LDV isolate that lacks neuropathogenicity, LDV-P, and the amino acid identifies of the predicted VP-3Ps of the two strains is 90%. Most striking, however, is the absence in the ectodomain...
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