This article is meant for, but not confined to, younger scientists who may have a series of ideas, hypotheses and projects – be they small or big – and might grapple with the objective to pursue and complete at least some, and preferably most, work in due course. And yet, the very generation, development and completion of numerous projects takes gestation periods which can be long and painful. Importantly, this simple but important truth is valid for any creative process, be it in the sciences or in the arts. With reference to luminaries like Max Perutz and George Wald, more general interfaces between science and the arts are identified. With reference to how some of Peter Doig’s paintings evolve over long times and to how John Eccles and Isaac Newton worked, extended gestation periods as a key similarity of creative work by both artists and scientists are exemplified and vindicated. It is concluded that long gestation periods of creative work should be viewed as the expectation rather than the exception. Importantly, the evolutionary and somewhat intuitive commitment to several projects at the same, and often extended, periods of time can be a recipe for revolutionary results fostered by the required variation and diversity of thinking and cross-fertilization of – seemingly – unrelated themes and fields.